PreMarket Price
Madrigal Pharmaceuticals, Inc. Common Stock (MDGL) logo

Madrigal Pharmaceuticals, Inc. Common Stock (MDGL)

Market Closed

Sector: Healthcare · Industry: Pharmaceutical Preparations

AnalystsStrong Buy24 analysts
Mkt Cap 11.86BROE -56.9%52wk $412.35–$602.83
Profilev32g0p0h75q5

What's happening with MDGL

Price History

5-Year Weekly Candlestick Chart

Profile

Valuation — 32/100 (Weak) P/E vs own history: n/a → 10/25 FCF yield: -2.3% → 0/25 P/S: 9.2x → 12/25 EV/EBIT: n/a → 10/25Valuation32Growth — 0/100 (Weak) Revenue CAGR: n/a → 0/25 Net income CAGR: n/a → 0/25 EPS CAGR 5Y: n/a → 0/25 Fwd implied growth: n/a → 0/25Growth0Profitability — 0/100 (Weak) ROIC: -348.8% → 0/25 ROE: -56.9% → 0/25 Net margin: -30.1% → 0/25 Operating margin: -31.6% → 0/25Profitability0Financial Health — 75/100 (Strong) Altman Z: 11.16 → 25/25 Current ratio: 3.50 → 25/25 Interest coverage: -163.1x → 0/25 Net cash / debt: Net cash → 25/25Health75Quality — 5/100 (Weak) Piotroski F: 2/9 → 5/25 Beneish M: n/a → 0/25 FCF conversion: n/a → 0/25 Margin stability: σ 815.4% → 0/25Quality5

Strong financial health; growth, profitability, earnings quality and valuation lag behind.

How is each axis scored?
  • Valuation32/100 · Weak
    • P/E vs own history (n/a)10/25
    • FCF yield (-2.3%)0/25
    • P/S (9.2x)12/25
    • EV/EBIT (n/a)10/25
  • Growth0/100 · Weak
    • Revenue CAGR (n/a)0/25
    • Net income CAGR (n/a)0/25
    • EPS CAGR 5Y (n/a)0/25
    • Fwd implied growth (n/a)0/25
  • Profitability0/100 · Weak
    • ROIC (-348.8%)0/25
    • ROE (-56.9%)0/25
    • Net margin (-30.1%)0/25
    • Operating margin (-31.6%)0/25
  • Financial Health75/100 · Strong
    • Altman Z (11.16)25/25
    • Current ratio (3.50)25/25
    • Interest coverage (-163.1x)0/25
    • Net cash / debt (Net cash)25/25
  • Quality5/100 · Weak
    • Piotroski F (2/9)5/25
    • Beneish M (n/a)0/25
    • FCF conversion (n/a)0/25
    • Margin stability (σ 815.4%)0/25

About Madrigal Pharmaceuticals, Inc. Common Stock

Madrigal Pharmaceuticals Inc is a biopharmaceutical company focused on delivering novel therapeutics for metabolic dysfunction-associated steatohepatitis (MASH), a serious liver disease with high unmet medical need that can lead to cirrhosis, liver failure, liver cancer, need for liver transplantation and premature mortality. Show more

Its medication, Rezdiffra (resmetirom), is a once-daily, oral, liver-directed thyroid hormone receptor beta agonist designed to target key underlying causes of MASH.

Headquarters: WEST CONSHOHOCKEN, PA · Employees: 915 · Website ↗

Insider Transactions

Recent SEC Form 4 filings

  • Sell
    Open market sale · filed 2026-09-11
    -120 sh
    2026-09-11
  • Sell
    Open market sale · filed 2026-09-11
    -761 sh
    2026-09-11
  • Sell
    Open market sale · filed 2026-09-11
    -1539 sh
    2026-09-11
  • Sell
    Open market sale · filed 2026-09-11
    -1202 sh
    2026-09-11
  • Sell
    Open market sale · filed 2026-09-11
    -368 sh
    2026-09-11

+3 more recent filings

Key Metrics

Financial snapshot — pillar inputs plus per-share and market context

Valuation

32D
P/E (TTM)—

Price / TTM EPS (own statements)

P/FCF124.7xD

Grade D: ExpensivePrice / Free Cash Flow per share (Finnhub). Inverse of FCF yield — negative when FCF is negative

FCF Yield-2.3%D

Grade D: NegativeTTM FCF / Market Cap — vs own 5Y history: -21.5%–-1.2% · 77th pct

P/S (TTM)9.24xC

Grade C: ExpensivePrice / TTM Revenue (own statements)

EV/EBITDA718.5xD

Grade D: ExpensiveEnterprise value / EBITDA (Finnhub) — capital-structure neutral

EV/Sales9.3xC

Grade C: ExpensiveEnterprise Value / TTM Revenue (Finnhub) — capital-structure neutral sales multiple

Forward P/E148.1xD

Grade D: ExpensivePrice / next-year EPS estimate — shows whether the TTM multiple is rich or just front-loading growth

P/B Ratio21.82xD

Grade D: Very expensivePrice to Book Value. Neg. equity = heavy buybacks

PEG Ratio-139.77A

Grade A: CheapFinnhub PEG — their P/E basis ÷ expected EPS growth. Suppressed when their P/E diverges >2× from our TTM P/E (different basis)

Dividend Yield—

TTM dividend yield (Finnhub) — annual dividends / price. None = no dividend; very high yield can signal distress

Payout Ratio—

Dividends / Net Income (Finnhub) — share of earnings paid out; >90% or negative = unsustainable

Profitability

0E
ROIC-348.8%D

Grade D: LowNOPAT (EBIT less ~21% tax) / invested capital (equity + debt − cash). Flagship quality metric — durable >15% signals a moat

ROE-56.9%D

Grade D: WeakReturn on Equity. Neg. equity = heavy buybacks

ROA-25.5%D

Grade D: WeakReturn on Assets (Finnhub) — Net Income / Total Assets; how efficiently assets produce profit

Net Margin-30.1%D

Grade D: LowNet Income / Revenue

Operating Margin—

TTM EBIT / TTM Revenue

Gross Margin94.1%A

Grade A: PremiumGross Profit / Revenue

FCF Margin—

FCF / Revenue

True FCF Margin—

TTM (OCF − CapEx − SBC) / TTM Revenue — SBC treated as a real cost

Financial Health

75B+
Altman Z-Score11.16A

Grade A: SafeBankruptcy risk. >3 Safe, <1.8 Distress

Current Ratio3.50xA

Grade A: HighCurrent Assets/Liabilities

Quick Ratio3.62xA

Grade A: High(Current Assets − Inventory) / Current Liabilities (Finnhub) — stricter liquidity test, excludes inventory

Interest Coverage-163.1xD

Grade D: RiskyEBIT/Interest. >10 Strong

Debt RepaymentNet CashA

Grade A: FastYears to repay net debt via FCF

Net Debt/EBIT1.5xA

Grade A: LowLeverage. <2x Low, >4x High

Debt/Equity0.63xA

Grade A: LowDebt / Equity: <1 Conservative, >2 Risky. Not meaningful with non-positive equity; shown as unavailable rather than low debt.

Cash / Debt2.39xA

Grade A: CoveredCash covers how much of total debt. >1 = could repay all debt from cash

Growth

0E
Revenue CAGR—

Compound annual revenue growth (up to 5Y depending on data availability)

Net Income CAGR—

Compound annual net income growth (up to 5Y depending on data availability)

EPS CAGR (5Y)—

Compound annual EPS growth over up to 5Y of per-share earnings (own statements). Null when either endpoint EPS ≤ 0

Implied EPS Growth—

Implied 1Y EPS growth from forward P/E vs our TTM EPS. Sparse — only where forward estimates exist

Dilution (5Y)—

Share count change over 5Y

SBC / Net Income—

Stock-based comp/Net income. >30% = dilution risk

SBC / Revenue—

TTM stock-based comp / TTM Revenue

Quality

10/10 Loss Years5E
Piotroski F-Score2/9D

Grade D: WeakFinancial strength 0–9. >7 Strong

Beneish M-Score—

Earnings manipulation risk. < -2.22 Safe

FCF Conversion—

FCF / Net Income

Margin Stability815.4%D

Grade D: VolatileEBIT margin std deviation. Lower = stable

Capex / Revenue—

TTM CapEx / TTM Revenue — high % = capital-hungry business

Asset Turnover0.76xC

Grade C: AverageRevenue / Total Assets (Finnhub) — how efficiently the asset base generates sales

More metrics — Per Share, Balance Sheet, Market

Per Share

EPS (TTM)—

TTM net income per share (Finnhub fallback)

Cash / Share$43.06

Cash & short-term investments per share (Finnhub)

Book Value / Share$26.39

Shareholders' equity per share (Finnhub). Negative = accumulated losses / heavy buybacks

Balance Sheet

Total Debt$340.33M

Total debt obligations (short + long term)

Cash & Equiv.$812.77M

Cash and short-term investments

Net Debt$-472.44MA

Grade A: Net CashTotal Debt minus Cash. Negative = Net Cash position

Total Equity$543.45M

Shareholders' equity (book value)

Asset / Liability1.79xC

Grade C: AdequateTotal Assets / Total Liabilities

Market

Market Cap$11.86B

Current Market Capitalization

Beta-1.09B

Grade B: DefensivePrice sensitivity vs the market (Finnhub) — 1.0 moves with market, >1.2 amplifies swings

Takeaway

Company is effectively debt-free after netting cash.

How grades work: each metric is graded A–D against fixed thresholds (tap a row for the meaning). Card grades map the pillar score to A+–E — a card grade is that pillar's own score, not an average of the rows shown.

Financials as of Mar 2026 · Ratio snapshot Sep 25, 2026

Key Insights: Madrigal Pharmaceuticals, Inc. Common Stock (MDGL)

Madrigal Pharmaceuticals, Inc. Common Stock meets only 2 of 9 Piotroski F-Score criteria — a sign of weak underlying fundamentals. Altman Z-Score of 11.16 sits comfortably in the safe zone (≥ 2.99), indicating low bankruptcy risk. Company is effectively debt-free after netting cash.

  • Interest coverage of -163.1× leaves little room for earnings shocks.
  • Madrigal Pharmaceuticals, Inc. Common Stock posted a net loss in 10 of 10 available completed fiscal years (2016–2025).

See how MDGL ranks on the Capex Tracker — top 50 capital spenders compared.

No significant market moves for MDGL in the last 30 days.

See MDGL move history →

Frequently Asked Questions about MDGL

Is MDGL stock a buy right now?

PreMarketPrice's quantitative model rates Madrigal Pharmaceuticals, Inc. Common Stock's financial health at 75/100. This is a data-driven snapshot of fundamentals, not investment advice.

Is MDGL stock overvalued?

Madrigal Pharmaceuticals, Inc. Common Stock trades at a trailing P/E of n/a and our valuation score rates it 32/100 (higher = cheaper vs. its own history). See the Valuation History and Key Metrics sections for forward P/E, EV/EBITDA and PEG context.

When does Madrigal Pharmaceuticals, Inc. Common Stock report earnings?

No confirmed earnings date is currently scheduled for MDGL. The Earnings section lists recent reports and updates as dates are announced.

What sector does Madrigal Pharmaceuticals, Inc. Common Stock operate in?

Madrigal Pharmaceuticals, Inc. Common Stock operates in the Healthcare sector, within the Pharmaceutical Preparations industry. The Related Stocks section lists sector peers for comparison.

What does Madrigal Pharmaceuticals, Inc. Common Stock do?

Madrigal Pharmaceuticals Inc is a biopharmaceutical company focused on delivering novel therapeutics for metabolic dysfunction-associated steatohepatitis (MASH), a serious liver disease with high unmet medical need that can lead to cirrhosis, liver failure, liver cancer, need for liver transplantation and premature mortality.

About Madrigal Pharmaceuticals, Inc. Common Stock (MDGL) Stock

Madrigal Pharmaceuticals, Inc. Common Stock (MDGL) is a US-listed stock operating in the Healthcare sector, specifically the Pharmaceutical Preparations industry. Real-time pricing data for Madrigal Pharmaceuticals, Inc. Common Stock is available on this page with a market capitalization of $11.9 billion. The financial health score for MDGL is 75/100, which indicates excellent financial strength based on profitability, leverage, liquidity, and growth metrics. This page provides real-time pre-market pricing, earnings calendar, financial health analysis, and valuation metrics for MDGL stock.

MDGL Stock Analysis & Key Metrics

On PreMarketPrice, you can track Madrigal Pharmaceuticals, Inc. Common Stock (MDGL) across multiple dimensions:

Is MDGL a Good Stock to Buy?

This page provides data-driven analysis to help you evaluate Madrigal Pharmaceuticals, Inc. Common Stock (MDGL) as an investment. The financial health score of 75/100 suggests excellent financial fundamentals. Valuation metrics show whether the stock is trading above or below its historical average.However, this is not financial advice — always do your own research before investing.

Data on this page is sourced from real-time market feeds, Polygon.io, and Finnhub.Madrigal Pharmaceuticals, Inc. Common Stock (MDGL) trades on NYSE/NASDAQ. Pre-market trading occurs 4:00 AM – 9:30 AM ET. Regular market hours are 9:30 AM – 4:00 PM ET.