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Twist Bioscience Corporation Common Stock (TWST)

Market Closed

Sector: Healthcare · Industry: Biological Products, (No Diagnostic Substances)

AnalystsStrong Buy16 analysts
Mkt Cap 12.20BROE -17.9%52wk $25.45–$184.03
Profilev20g25p0h75q35

What's happening with TWST

Price History

5-Year Weekly Candlestick Chart

Profile

Valuation — 20/100 (Weak) P/E vs own history: n/a → 10/25 FCF yield: -0.8% → 0/25 P/S: 29.8x → 0/25 EV/EBIT: n/a → 10/25Valuation20Growth — 25/100 (Weak) Revenue CAGR: 29.9% → 25/25 Net income CAGR: n/a → 0/25 EPS CAGR 5Y: n/a → 0/25 Fwd implied growth: n/a → 0/25Growth25Profitability — 0/100 (Weak) ROIC: -38.7% → 0/25 ROE: -17.9% → 0/25 Net margin: -19.8% → 0/25 Operating margin: -33.9% → 0/25Profitability0Financial Health — 75/100 (Strong) Altman Z: 28.06 → 25/25 Current ratio: 2.70 → 25/25 Interest coverage: -235.7x → 0/25 Net cash / debt: Net cash → 25/25Health75Quality — 35/100 (Weak) Piotroski F: 4/9 → 10/25 Beneish M: -2.67 → 25/25 FCF conversion: n/a → 0/25 Margin stability: σ 69.4% → 0/25Quality35

Strong financial health; profitability, valuation, growth and earnings quality lag behind.

How is each axis scored?
  • Valuation20/100 · Weak
    • P/E vs own history (n/a)10/25
    • FCF yield (-0.8%)0/25
    • P/S (29.8x)0/25
    • EV/EBIT (n/a)10/25
  • Growth25/100 · Weak
    • Revenue CAGR (29.9%)25/25
    • Net income CAGR (n/a)0/25
    • EPS CAGR 5Y (n/a)0/25
    • Fwd implied growth (n/a)0/25
  • Profitability0/100 · Weak
    • ROIC (-38.7%)0/25
    • ROE (-17.9%)0/25
    • Net margin (-19.8%)0/25
    • Operating margin (-33.9%)0/25
  • Financial Health75/100 · Strong
    • Altman Z (28.06)25/25
    • Current ratio (2.70)25/25
    • Interest coverage (-235.7x)0/25
    • Net cash / debt (Net cash)25/25
  • Quality35/100 · Weak
    • Piotroski F (4/9)10/25
    • Beneish M (-2.67)25/25
    • FCF conversion (n/a)0/25
    • Margin stability (σ 69.4%)0/25

About Twist Bioscience Corporation Common Stock

Twist Bioscience Corp is a synthetic biology company that has developed a disruptive DNA synthesis platform to industrialize the engineering of biology. Show more

The company's proprietary semiconductor-based manufacturing process synthesizes DNA on silicon rather than traditional plastic plates, enabling the production of high-quality synthetic DNA faster, more affordably, and at scale. This platform overcomes conventional inefficiencies, supports cost-effective, high-throughput synthesis, and allows researchers to accelerate innovation. Geographically, the company operates across the Americas, EMEA, and APAC, deriving the majority of its revenue from the Americas.

Headquarters: SOUTH SAN FRANCISCO, CA · Employees: 979 · Website ↗

Insider Transactions

Recent SEC Form 4 filings

  • Sell
    Open market sale · filed 2026-09-23
    -348 sh
    2026-09-21
  • Sell
    Open market sale · filed 2026-09-23
    -294 sh
    2026-09-21
  • Sell
    Open market sale · filed 2026-09-23
    -1687 sh
    2026-09-21
  • Sell
    Option exercise · filed 2026-09-21
    -133269 sh
    2026-09-17
  • Sell
    Option exercise · filed 2026-09-21
    -75439 sh
    2026-09-17

+3 more recent filings

Key Metrics

Financial snapshot — pillar inputs plus per-share and market context

Valuation

20E
P/E (TTM)—

Price / TTM EPS (own statements)

P/FCF—

Price / Free Cash Flow per share (Finnhub). Inverse of FCF yield — negative when FCF is negative

FCF Yield-0.8%D

Grade D: NegativeTTM FCF / Market Cap — vs own 5Y history: -32.6%–-0.8% · highest in history

P/S (TTM)29.79xD

Grade D: ExpensivePrice / TTM Revenue (own statements) — vs own 5Y history: 2.9x–27.6x · highest in history

EV/EBITDA—

Enterprise value / EBITDA (Finnhub) — capital-structure neutral

EV/Sales27.8xD

Grade D: Very expensiveEnterprise Value / TTM Revenue (Finnhub) — capital-structure neutral sales multiple

Forward P/E—

Price / next-year EPS estimate — shows whether the TTM multiple is rich or just front-loading growth

P/B Ratio26.81xD

Grade D: Very expensivePrice to Book Value. Neg. equity = heavy buybacks

PEG Ratio-1.34A

Grade A: CheapFinnhub PEG — their P/E basis ÷ expected EPS growth. Suppressed when their P/E diverges >2× from our TTM P/E (different basis)

Dividend Yield—

TTM dividend yield (Finnhub) — annual dividends / price. None = no dividend; very high yield can signal distress

Payout Ratio—

Dividends / Net Income (Finnhub) — share of earnings paid out; >90% or negative = unsustainable

Profitability

0E
ROIC-38.7%D

Grade D: LowNOPAT (EBIT less ~21% tax) / invested capital (equity + debt − cash). Flagship quality metric — durable >15% signals a moat

ROE-17.9%D

Grade D: WeakReturn on Equity. Neg. equity = heavy buybacks

ROA-20.8%D

Grade D: WeakReturn on Assets (Finnhub) — Net Income / Total Assets; how efficiently assets produce profit

Net Margin-19.8%D

Grade D: LowNet Income / Revenue

Operating Margin-33.9%D

Grade D: LowTTM EBIT / TTM Revenue

Gross Margin52.1%A

Grade A: PremiumGross Profit / Revenue

FCF Margin-23.2%D

Grade D: LowFCF / Revenue

True FCF Margin-38.9%D

Grade D: LowTTM (OCF − CapEx − SBC) / TTM Revenue — SBC treated as a real cost

Financial Health

75B+
Altman Z-Score28.06A

Grade A: SafeBankruptcy risk. >3 Safe, <1.8 Distress

Current Ratio2.70xA

Grade A: HighCurrent Assets/Liabilities

Quick Ratio3.17xA

Grade A: High(Current Assets − Inventory) / Current Liabilities (Finnhub) — stricter liquidity test, excludes inventory

Interest Coverage-235.7xD

Grade D: RiskyEBIT/Interest. >10 Strong

Debt RepaymentNet CashA

Grade A: FastYears to repay net debt via FCF

Net Debt/EBIT—

Leverage. <2x Low, >4x High

Debt/Equity0.00xA

Grade A: LowDebt / Equity: <1 Conservative, >2 Risky. Not meaningful with non-positive equity; shown as unavailable rather than low debt.

Cash / Debt—

Cash covers how much of total debt. >1 = could repay all debt from cash

Growth

25E
Revenue CAGR29.9%A

Grade A: HighCompound annual revenue growth (up to 5Y depending on data availability)

Net Income CAGR—

Compound annual net income growth (up to 5Y depending on data availability)

EPS CAGR (5Y)—

Compound annual EPS growth over up to 5Y of per-share earnings (own statements). Null when either endpoint EPS ≤ 0

Implied EPS Growth—

Implied 1Y EPS growth from forward P/E vs our TTM EPS. Sparse — only where forward estimates exist

Dilution (5Y)—

Share count change over 5Y

SBC / Net Income—

Stock-based comp/Net income. >30% = dilution risk

SBC / Revenue15.7%D

Grade D: HighTTM stock-based comp / TTM Revenue

Quality

7/7 Loss Years35D
Piotroski F-Score4/9C

Grade C: AverageFinancial strength 0–9. >7 Strong

Beneish M-Score-2.67A

Grade A: SafeEarnings manipulation risk. < -2.22 Safe

FCF Conversion—

FCF / Net Income

Margin Stability69.4%D

Grade D: VolatileEBIT margin std deviation. Lower = stable

Capex / Revenue9.6%C

Grade C: AverageTTM CapEx / TTM Revenue — high % = capital-hungry business

Asset Turnover0.59xC

Grade C: AverageRevenue / Total Assets (Finnhub) — how efficiently the asset base generates sales

More metrics — Per Share, Balance Sheet, Market

Per Share

EPS (TTM)—

TTM net income per share (Finnhub fallback)

Cash / Share$3.83

Cash & short-term investments per share (Finnhub)

Book Value / Share$7.80

Shareholders' equity per share (Finnhub). Negative = accumulated losses / heavy buybacks

Balance Sheet

Total Debt—

Total debt obligations (short + long term)

Cash & Equiv.$171.67M

Cash and short-term investments

Net Debt—

Total Debt minus Cash. Negative = Net Cash position

Total Equity$455.09M

Shareholders' equity (book value)

Asset / Liability3.06xA

Grade A: SolidTotal Assets / Total Liabilities

Market

Market Cap$12.20B

Current Market Capitalization

Beta2.25D

Grade D: High volatilityPrice sensitivity vs the market (Finnhub) — 1.0 moves with market, >1.2 amplifies swings

Takeaway

Company is effectively debt-free after netting cash.

How grades work: each metric is graded A–D against fixed thresholds (tap a row for the meaning). Card grades map the pillar score to A+–E — a card grade is that pillar's own score, not an average of the rows shown.

Financials as of Mar 2026 · Ratio snapshot Sep 25, 2026

Key Insights: Twist Bioscience Corporation Common Stock (TWST)

Piotroski F-Score of 4/9 indicates mixed fundamentals for Twist Bioscience Corporation Common Stock. Altman Z-Score of 28.06 sits comfortably in the safe zone (≥ 2.99), indicating low bankruptcy risk. Beneish M-Score of -2.67 suggests a low likelihood of earnings manipulation. Revenue has compounded at roughly 30% annually — a strong growth profile. Free-cash-flow margin is negative (-23%) — the business currently burns cash.

  • Company is effectively debt-free after netting cash.
  • Interest coverage of -235.7× leaves little room for earnings shocks.
  • Twist Bioscience Corporation Common Stock posted a net loss in 7 of 7 available completed fiscal years (2019–2025).
  • At a valuation score of 20/100, TWST trades at a premium to its historical multiples.

See how TWST ranks on the Capex Tracker — top 50 capital spenders compared.

Recent Market Moves

See all TWST moves →
DateSessionPriceMoveZ-Score
Sep 24Regular182.89+15.39%3.44
Sep 24After-hours184.05+16.12%3.59

Frequently Asked Questions about TWST

Is TWST stock a buy right now?

PreMarketPrice's quantitative model rates Twist Bioscience Corporation Common Stock's financial health at 75/100. This is a data-driven snapshot of fundamentals, not investment advice.

Is TWST stock overvalued?

Twist Bioscience Corporation Common Stock trades at a trailing P/E of n/a and our valuation score rates it 20/100 (higher = cheaper vs. its own history). See the Valuation History and Key Metrics sections for forward P/E, EV/EBITDA and PEG context.

When does Twist Bioscience Corporation Common Stock report earnings?

No confirmed earnings date is currently scheduled for TWST. The Earnings section lists recent reports and updates as dates are announced.

What sector does Twist Bioscience Corporation Common Stock operate in?

Twist Bioscience Corporation Common Stock operates in the Healthcare sector, within the Biological Products, (No Diagnostic Substances) industry. The Related Stocks section lists sector peers for comparison.

What does Twist Bioscience Corporation Common Stock do?

Twist Bioscience Corp is a synthetic biology company that has developed a disruptive DNA synthesis platform to industrialize the engineering of biology.

About Twist Bioscience Corporation Common Stock (TWST) Stock

Twist Bioscience Corporation Common Stock (TWST) is a US-listed stock operating in the Healthcare sector, specifically the Biological Products, (No Diagnostic Substances) industry. Real-time pricing data for Twist Bioscience Corporation Common Stock is available on this page with a market capitalization of $12.2 billion. The financial health score for TWST is 75/100, which indicates excellent financial strength based on profitability, leverage, liquidity, and growth metrics. This page provides real-time pre-market pricing, earnings calendar, financial health analysis, and valuation metrics for TWST stock.

TWST Stock Analysis & Key Metrics

On PreMarketPrice, you can track Twist Bioscience Corporation Common Stock (TWST) across multiple dimensions:

Is TWST a Good Stock to Buy?

This page provides data-driven analysis to help you evaluate Twist Bioscience Corporation Common Stock (TWST) as an investment. The financial health score of 75/100 suggests excellent financial fundamentals. Valuation metrics show whether the stock is trading above or below its historical average.However, this is not financial advice — always do your own research before investing.

Data on this page is sourced from real-time market feeds, Polygon.io, and Finnhub.Twist Bioscience Corporation Common Stock (TWST) trades on NYSE/NASDAQ. Pre-market trading occurs 4:00 AM – 9:30 AM ET. Regular market hours are 9:30 AM – 4:00 PM ET.