Pre-market price movements and significant market activity for AstraZeneca PLC ($AZN). Each move is flagged by Z-score statistical significance — showing when $AZN moved beyond its typical daily range. 2 significant moves detected in the last 30 days.
Current Market State
What May Be Driving AZN?
Citi's $4.4bn peak sales estimate for efzimfotase alfa and FDA NDA submission for the lung cancer combo.
AstraZeneca PLC operates in the Healthcare sector, specifically Drug Manufacturers - General. Sector-wide movement can contribute to individual stock volatility.
Recent Unusual Moves (30 days)
| Date | Session | Price | Move | Z-Score | Rel. Vol. |
|---|---|---|---|---|---|
| Oct 14, 2026 | Regular | $162.31 | +4.17% | 3.33 | 0.8× |
| Sep 23, 2026 | Regular | $163.63 | -2.82% | -2.11 | 0.5× |
About AZN Premarket Movers
This page tracks unusual market activity for AstraZeneca PLC (AZN) across all trading sessions — pre-market (4:00 AM–9:30 AM ET), regular hours (9:30 AM–4:00 PM ET), and after-hours (4:00 PM–8:00 PM ET). A move is flagged as "unusual" when its Z-score reaches 2 or higher, meaning the price change is statistically significant relative to AZN's recent daily volatility.
Z-score is calculated by comparing each move to the 20-day average return and standard deviation. A Z-score of 2.0 means the move is 2 standard deviations beyond the average — occurring in roughly the top 5% of daily moves. Relative volume (RVOL) compares current volume to the 20-day average volume at the same time of day, helping distinguish genuine institutional activity from noise.