PreMarket Price
PreMarket Price
Madrigal Pharmaceuticals, Inc. Common Stock (MDGL) logo

Stock Analysis

Madrigal Pharmaceuticals, Inc. Common StockMDGL

Price:$449.74Market Closed-2.19%at last close

Sector: Healthcare · Industry: Pharmaceutical Preparations

AnalystsStrong Buy24 analysts
Mkt Cap 10.34BROE -62.1%
Low $412.35$449.74High $602.83

Price is 20% of the way from the year's low to its high.

Cash $0.84BNet cash $0.49BDebt $0.35B

Cash covers 241% of debt · Q2 2026.

Profilev32g0p0h75q5m0

PMP Verdict

Cheap for a reason — weak fundamentals

Strengths

  • Financial Health75

Risks

  • Growth0
  • Profitability0
P/S 0th percentile

Cheap for a reason — fundamentals remain weak.

Market context

-2.2% today· Z 1.8σ

Bull Case

  • ✓Altman Z 9.3 — safe-zone balance sheet

What's happening with MDGL

Profile

Valuation — 32/100 (Weak) P/E vs own history: n/a → 10/25 FCF yield: -2.0% → 0/25 P/S: 8.1x → 12/25 EV/EBIT: n/a → 10/25Valuation32Growth — 0/100 (Weak) Revenue CAGR: n/a → 0/25 Net income CAGR: n/a → 0/25 EPS CAGR 5Y: n/a → 0/25 Fwd implied growth: n/a → 0/25Growth0Profitability — 0/100 (Weak) ROIC: -778.9% → 0/25 ROE: -62.1% → 0/25 Net margin: -25.3% → 0/25 Operating margin: -25.1% → 0/25Profitability0Financial Health — 75/100 (Strong) Altman Z: 9.25 → 25/25 Current ratio: 3.20 → 25/25 Interest coverage: -24.1x → 0/25 Net cash / debt: Net cash → 25/25Health75Quality — 5/100 (Weak) Piotroski F: 3/9 → 5/25 Beneish M: 0.14 → 0/25 FCF conversion: n/a → 0/25 Margin stability: σ 656.5% → 0/25Quality5Moat — 0/100 (Weak) ROIC >12% years: n/a → 0/25 Median gross margin: n/a → 0/25 FCF-positive years: 0/10 yrs → 0/25 Worst-year net margin: n/a → 0/25Moat0

Strong financial health; growth, profitability, moat, earnings quality and valuation lag behind.

How is each axis scored?
  • Valuation32/100 · Weak
    • P/E vs own history (n/a)10/25
    • FCF yield (-2.0%)0/25
    • P/S (8.1x)12/25
    • EV/EBIT (n/a)10/25
  • Growth0/100 · Weak
    • Revenue CAGR (n/a)0/25
    • Net income CAGR (n/a)0/25
    • EPS CAGR 5Y (n/a)0/25
    • Fwd implied growth (n/a)0/25
  • Profitability0/100 · Weak
    • ROIC (-778.9%)0/25
    • ROE (-62.1%)0/25
    • Net margin (-25.3%)0/25
    • Operating margin (-25.1%)0/25
  • Financial Health75/100 · Strong
    • Altman Z (9.25)25/25
    • Current ratio (3.20)25/25
    • Interest coverage (-24.1x)0/25
    • Net cash / debt (Net cash)25/25
  • Quality5/100 · Weak
    • Piotroski F (3/9)5/25
    • Beneish M (0.14)0/25
    • FCF conversion (n/a)0/25
    • Margin stability (σ 656.5%)0/25
  • Moat0/100 · Weak
    • ROIC >12% years (n/a)0/25
    • Median gross margin (n/a)0/25
    • FCF-positive years (0/10 yrs)0/25
    • Worst-year net margin (n/a)0/25

Risk Flags

  • ⚠Beneish M 0.14 — earnings-manipulation flag
  • ⚠Negative FCF margin (-0.2%) — burning cash
  • ⚠SBC 9.5% of revenue — real dilution cost
  • ⚠10 loss-making years in recent history
  • ⚠Interest coverage -24.1× — thin debt cushion

About Madrigal Pharmaceuticals, Inc. Common Stock

Madrigal Pharmaceuticals Inc is a biopharmaceutical company focused on delivering novel therapeutics for metabolic dysfunction-associated steatohepatitis (MASH), a serious liver disease with high unmet medical need that can lead to cirrhosis, liver failure, liver cancer, need for liver transplantation and premature mortality. Show more

Its medication, Rezdiffra (resmetirom), is a once-daily, oral, liver-directed thyroid hormone receptor beta agonist designed to target key underlying causes of MASH.

Headquarters: WEST CONSHOHOCKEN, PA · Employees: 915 · Website ↗

Price History

Weekly Candlestick Chart — up to 5Y

Key Metrics

Financial snapshot · Tap any metric for its definition and grade

TTM Snapshot

trailing twelve months · YoY
Revenue
1.3B+149%
Op. Income
-322.6M
Net Income
-325.1M
EPS
-11.2
Operating CF
-197.7M
Free CF
-206.3M

Valuation

32D
P/E (TTM)—

Price / TTM EPS (own statements)

P/FCF112.2xD

Grade D: ExpensivePrice / Free Cash Flow per share (Finnhub). Inverse of FCF yield — negative when FCF is negative

FCF Yield-2.0%D

Grade D: NegativeTTM (OCF − CapEx) / Market Cap — vs own 5Y history: -21.5%–-1.2% · 76th pct

P/S (TTM)8.05xC

Grade C: ExpensivePrice / TTM Revenue (own statements) — vs own 5Y history: 8.1x–54.9x · lowest in history

EV/EBITDA646.7xD

Grade D: ExpensiveEnterprise value / EBITDA (Finnhub) — capital-structure neutral

EV/Sales8.3xC

Grade C: ExpensiveEnterprise Value / TTM Revenue (Finnhub) — capital-structure neutral sales multiple

Forward P/E148.1xD

Grade D: ExpensivePrice / next-year EPS estimate — shows whether the TTM multiple is rich or just front-loading growth

P/B Ratio19.74xD

Grade D: Very expensivePrice to Book Value. Neg. equity = heavy buybacks

PEG Ratio-125.27A

Grade A: CheapFinnhub PEG — their P/E basis ÷ expected EPS growth. Suppressed when their P/E diverges >2× from our TTM P/E (different basis)

Dividend Yield—

TTM dividend yield (Finnhub) — annual dividends / price. None = no dividend; very high yield can signal distress

Payout Ratio—

Dividends / Net Income (Finnhub) — share of earnings paid out; >90% or negative = unsustainable

Profitability

0E
ROIC-778.9%D

Grade D: LowNOPAT (EBIT less ~21% tax) / invested capital (equity + debt − cash). Flagship quality metric — durable >15% signals a moat

ROE-62.1%D

Grade D: WeakReturn on Equity. Neg. equity = heavy buybacks

ROA-25.5%D

Grade D: WeakReturn on Assets (Finnhub) — Net Income / Total Assets; how efficiently assets produce profit

Net Margin-25.3%D

Grade D: LowNet Income / Revenue

Operating Margin-25.1%D

Grade D: LowTTM EBIT / TTM Revenue

Gross Margin91.5%A

Grade A: PremiumGross Profit / Revenue

FCF Margin-16.1%D

Grade D: LowFCF / Revenue

True FCF Margin-25.5%D

Grade D: LowTTM (OCF − CapEx − SBC) / TTM Revenue — SBC treated as a real cost

Growth

0E
Revenue CAGR—

Compound annual revenue growth (up to 5Y depending on data availability)

Net Income CAGR—

Compound annual net income growth (up to 5Y depending on data availability)

EPS CAGR (5Y)—

Compound annual EPS growth over up to 5Y of per-share earnings (own statements). Null when either endpoint EPS ≤ 0

Implied EPS Growth—

Analyst forward EPS (normalized basis) vs our GAAP TTM EPS — different bases, so extreme values usually mark cyclically depressed TTM earnings, not real growth

Dilution (5Y)—

Share count change over 5Y

SBC / Net Income—

Stock-based comp/Net income. >30% = dilution risk

SBC / Revenue9.5%D

Grade D: HighTTM stock-based comp / TTM Revenue

Financial Health

75B+
Altman Z-Score9.25A

Grade A: SafeBankruptcy risk. >3 Safe, <1.8 Distress

Current Ratio3.20xA

Grade A: HighCurrent Assets/Liabilities

Quick Ratio2.76xA

Grade A: High(Current Assets − Inventory) / Current Liabilities (Finnhub) — stricter liquidity test, excludes inventory

Interest Coverage-24.1xD

Grade D: RiskyEBIT/Interest. >10 Strong

Debt RepaymentNet CashA

Grade A: FastYears to repay net debt via FCF

Net Debt/EBIT1.5xA

Grade A: LowLeverage. <2x Low, >4x High

Debt/Equity0.66xA

Grade A: LowDebt / Equity: <1 Conservative, >2 Risky. Not meaningful with non-positive equity; shown as unavailable rather than low debt.

Cash / Debt2.41xA

Grade A: CoveredCash covers how much of total debt. >1 = could repay all debt from cash

Quality

5E
Piotroski F-Score3/9D

Grade D: WeakFinancial strength 0–9. >7 Strong

Beneish M-Score0.14D

Grade D: RiskyEarnings manipulation risk. < -2.22 Safe

FCF Conversion—

FCF / Net Income

Margin Stability656.5%D

Grade D: VolatileEBIT margin std deviation. Lower = stable

Capex / Revenue0.7%A

Grade A: Asset-lightTTM CapEx / TTM Revenue — high % = capital-hungry business

Asset Turnover1.01xA

Grade A: HighRevenue / Total Assets (Finnhub) — how efficiently the asset base generates sales

10/10 Loss Years

Insider Transactions

SEC Form 4 · 8 records
Open-market · 90dBuy —Sell $3.8M (15)Net open-market selling

P/S codes are the directional signal; grants, option exercises and tax withholding carry none. Form 4 doesn't flag 10b5-1 plans — scheduled sales may appear within open-market sells.

Recent insider transactions
Trade dateTransactionShares
Sibold William John
Filed
SellOpen market sale
-120
Sibold William John
Filed
SellOpen market sale
-761
Sibold William John
Filed
SellOpen market sale
-1539
Sibold William John
Filed
SellOpen market sale
-1202
Sibold William John
Filed
SellOpen market sale
-368
Show 3 more filings
Additional recent insider transactions
Trade dateTransactionShares
Sibold William John
Filed
SellOpen market sale
-687
Sibold William John
Filed
SellOpen market sale
-160
Sibold William John
Filed
SellOpen market sale
-218
More metrics — Moat, Per Share, Balance Sheet, Market

Moat

0E
ROIC >12% Years—

Share of completed fiscal years with ROIC > 12% — measures multi-year capital-return durability

Gross Margin (Med.)—

Median annual gross margin across available fiscal years — pricing-power durability

FCF-Positive Years0/10 yrsD

Grade D: WeakShare of completed fiscal years with positive free cash flow

Net Margin Floor—

Weakest annual net margin across completed fiscal years — recession/downcycle resilience

Per Share

EPS (TTM)—

TTM net income per share (Finnhub fallback)

Cash / Share$36.32

Cash & short-term investments per share (Finnhub)

Book Value / Share$22.68

Shareholders' equity per share (Finnhub). Negative = accumulated losses / heavy buybacks

Balance Sheet

Total Debt$347.75M

Total debt obligations (short + long term)

Cash & Equiv.$838.75M

Cash and short-term investments

Net Debt$-491.00MA

Grade A: Net CashTotal Debt minus Cash. Negative = Net Cash position

Total Equity$523.72M

Shareholders' equity (book value)

Asset / Liability1.73xC

Grade C: AdequateTotal Assets / Total Liabilities

Market

Market Cap$10.34B

Current Market Capitalization

Beta-1.09B

Grade B: DefensivePrice sensitivity vs the market (Finnhub) — 1.0 moves with market, >1.2 amplifies swings

How grades work: each metric is graded A–D against fixed thresholds (tap a row for the meaning). Card grades map the pillar score to A+–E — a card grade is that pillar's own score, not an average of the rows shown.

Financials as of Jun 2026 · Ratio snapshot Oct 17, 2026

Key Insights: Madrigal Pharmaceuticals, Inc. Common Stock (MDGL)

MDGL is down 2.19% at the last close. Madrigal Pharmaceuticals, Inc. Common Stock meets only 3 of 9 Piotroski F-Score criteria — a sign of weak underlying fundamentals. Altman Z-Score of 9.25 sits comfortably in the safe zone (≥ 2.99), indicating low bankruptcy risk. Beneish M-Score of 0.14 is above the −1.78 flag threshold, a signal that reported earnings warrant closer scrutiny.

  • Free-cash-flow margin is negative (-16%) — the business currently burns cash.
  • Company is effectively debt-free after netting cash.
  • Interest coverage of -24.1× leaves little room for earnings shocks.
  • Madrigal Pharmaceuticals, Inc. Common Stock posted a net loss in 10 of 10 available completed fiscal years (2016–2025).

See how MDGL ranks on the Capex Tracker — top 50 capital spenders compared.

Recent Market Moves

See all MDGL moves →
DateSessionPriceMoveZ-Score
Oct 14Regular458.79+1.47%2.23
Oct 14After-hours460.01+1.75%2.49
Oct 13Regular454.20-2.77%-2.35
Oct 13After-hours452.12-3.22%-2.83

Frequently Asked Questions about MDGL

What is the current Madrigal Pharmaceuticals, Inc. Common Stock (MDGL) stock price?

MDGL is trading at $449.74 at the last market close, down 2.19% on the session. PreMarketPrice tracks MDGL pre-market, intraday and after-hours prices.

Is MDGL stock a buy right now?

PreMarketPrice's quantitative model rates Madrigal Pharmaceuticals, Inc. Common Stock's financial health at 75/100. This is a data-driven snapshot of fundamentals, not investment advice.

Is MDGL stock overvalued?

Madrigal Pharmaceuticals, Inc. Common Stock trades at a trailing P/E of n/a and our valuation score rates it 32/100 (higher = cheaper vs. its own history). See the Valuation History and Key Metrics sections for forward P/E, EV/EBITDA and PEG context.

When does Madrigal Pharmaceuticals, Inc. Common Stock report earnings?

No confirmed earnings date is currently scheduled for MDGL. The Earnings section lists recent reports and updates as dates are announced.

What sector does Madrigal Pharmaceuticals, Inc. Common Stock operate in?

Madrigal Pharmaceuticals, Inc. Common Stock operates in the Healthcare sector, within the Pharmaceutical Preparations industry. The Related Stocks section lists sector peers for comparison.

What does Madrigal Pharmaceuticals, Inc. Common Stock do?

Madrigal Pharmaceuticals Inc is a biopharmaceutical company focused on delivering novel therapeutics for metabolic dysfunction-associated steatohepatitis (MASH), a serious liver disease with high unmet medical need that can lead to cirrhosis, liver failure, liver cancer, need for liver transplantation and premature mortality.

About Madrigal Pharmaceuticals, Inc. Common Stock (MDGL) Stock

Madrigal Pharmaceuticals, Inc. Common Stock (MDGL) is a US-listed stock operating in the Healthcare sector, specifically the Pharmaceutical Preparations industry. As of the latest update, Madrigal Pharmaceuticals, Inc. Common Stock is trading at $449.74, down 2.19% on the day with a market capitalization of $10.3 billion. The financial health score for MDGL is 75/100, which indicates excellent financial strength based on profitability, leverage, liquidity, and growth metrics. This page provides real-time pre-market pricing, earnings calendar, financial health analysis, and valuation metrics for MDGL stock.

MDGL Stock Analysis & Key Metrics

On PreMarketPrice, you can track Madrigal Pharmaceuticals, Inc. Common Stock (MDGL) across multiple dimensions:

Is MDGL a Good Stock to Buy?

This page provides data-driven analysis to help you evaluate Madrigal Pharmaceuticals, Inc. Common Stock (MDGL) as an investment. The financial health score of 75/100 suggests excellent financial fundamentals. Valuation metrics show whether the stock is trading above or below its historical average.However, this is not financial advice — always do your own research before investing.

Data on this page is sourced from real-time market feeds, Polygon.io, and Finnhub.Madrigal Pharmaceuticals, Inc. Common Stock (MDGL) trades on NYSE/NASDAQ. Pre-market trading occurs 4:00 AM – 9:30 AM ET. Regular market hours are 9:30 AM – 4:00 PM ET.

Related opportunities

Moving today in Healthcare
More Pharmaceutical Preparations stocks
Cheaper alternatives
Similar fundamentals